A four-channel Voltage/Current clamp apparatus, EVC4000 employs the voltage clamp technique to monitor membrane permeability as a function of membrane voltage or applied chemicals. When combined with WPI's patented EKC and EKV cartridge electrodes, EVC4000 can efficiently voltage or current clamp up to four sample membranes simultaneously using safe moderate voltages on the current wire leads.

Extremely stable and accurate, each module, with its companion preamplifier, can operate independently in one of three different modes: Voltage Clamp (VC), Current Clamp (CC), or Open Circuit Potential (PD) measurement. EVC4000 can be controlled from the front panel of the instrument or from computer generated commands applied at the rear panel of the instrument.

A feature unique to EVC4000 is an electronic potentiostat in the preamplifier box that maintains the serosal electrode invariant's potential at zero relative to system ground. The preamplifier apparatus actively maintains one surface of the test membrane close to ground potential under all operating conditions.

Pro 4™, a versatile, general-purpose timer/controller, can completely control the functions of the EVC4000.