They are excellent microinjection and perfusion engines for pharmacological drug testing, molecular biological DNA, RNA transferring, intracytoplasmic sperm injection and cell electrophysiological applications. Combining an advanced microcontroller and precise pneumatic components, these systems can simultaneously control up to eight injection micropipettes or eight perfusion vials and one cell holding pipette and one drain pipette.
The four (PM2000B) or eight (PM8000) injection/perfusion output ports can be controlled separately or combined together to perform actions such as injection, capillary action balancing, suction or clear up. The cell holding output port can produce an adjusted gentle suction to hold a cell or eject a pressure to push a cell or completely clear the holding pipette. Another drain output port can simultaneously produce an adjusted suction to drain and clear out liquid before next channel microperfusion. Both PM2000B and PM8000 can deliver different quantity agents and drugs from picoliters to continued perfusion.
All output pressures and vacuums are regulatable and can be real-time displayed on the front panel display. Previous pressure readings can also be recovered on the display for setting comparison.
Besides programmable timers and counters, there are 16 programmable and saveable injection/perfusion sequences with 32 programmable steps in each sequence. Each sequence can be repeated continually or triggered manually. The interval time between steps can be programmed for automatic sequential cycle or manual trigger.
There are two foot switch connectors for sequential step trigger and injection trigger. A digital remote port can be connected to an optional remote key pad, or be controlled by a computer. With exceptional versatility and extremely precise control, both PM2000B and PM8000 are ideal multichannel injection / perfusion engines.

Extracellular Microperfusion Setup

Intracellular Injection Setup