Vibroslice uses a vibrating blade to slice tissues without the trauma produced by other methods. Live brain or other tissues can be cut into slices 50- to 700-microns thick. Fixed tissues can be cut down to 20-micron slices (these need not be embedded or frozen). Particularly useful for improving the access for certain histological reagents (e.g., during processing for horseradish peroxidase).

The blade has a lateral displacement of about 1 mm, and its oscillating frequency may be varied between 60 and 4500 rpm. This allows you to achieve clean cuts in tissues of different mechanical consistencies.

Model NVSL offers a manual advance for positioning the specimen holder and bath chamber. Sample positioning on Model VSLM1 is motorized. Other features include independent, removable specimen holder and bath chamber, variable advance speed (motorized 0.07 - 1.6 mm/s version only) and hands-free operation via a footswitch.

IntegraSlice

The unprecedented quality of slice of IntegraSlice stems from its technical design features including cutting head mounted upon a parallel leaf-spring assuring blade travel along a line and arcuate path of the blade avoiding static contact of the blade with the advancing tissue. Sophisticated control allows the advance speed to be varied from minus 1.00mm/sec and up to 3.00mm/sec in steps of 0.01mm. During blade return the machine automatically lowers the tissue away from the blade and then readjusts to the original height once blade retraction has been completed. In all operations, even at the slowest rates, blade advance and blade speed is accurately maintained exactly as the user has specified due to constant feedback control. Slice thickness can be incremented in 1 micron steps and controlled to a maximum speed of 1 micron per second.

The unprecedented quality of slice of IntegraSlice stems from its technical design features including cutting head mounted upon a parallel leaf-spring assuring blade travel along a line and arcuate path of the blade avoiding static contact of the blade with the advancing tissue. Sophisticated control allows the advance speed to be varied from minus 1.00mm/sec and up to 3.00mm/sec in steps of 0.01mm. During blade return the machine automatically lowers the tissue away from the blade and then readjusts to the original height once blade retraction has been completed. In all operations, even at the slowest rates, blade advance and blade speed is accurately maintained exactly as the user has specified due to constant feedback control. Slice thickness can be incremented in 1 micron steps and controlled to a maximum speed of 1 micron per second.

Two Models Available:

IntegraSlice-P— Fully programmable cutting profiles of speed, distance, section thickness

• Dynamically Adjustable Speed and Amplitude (DASA) - both the speed and the amplitude of the cut can be dynamically adjusted, whilst the blade is in motion

• Instrument “learns” manually controlled cycle, which can be repeated automatically

• Cutting profiles can be set and stored

IntegraSlice-M— Motorized or Manual advance of the oscillating blade

• A set speed motorized advance or manual advanced controlled by rotary knob dial

IntegraSlice design combines accuracy, speed and the flexibility to remove the tissue bath and mounting for transport of the tissue, for cleaning and autoclaving. integraslice is supplied with a standard tissue bath and holder, which can be replaced by the autoclavable version or the temperature controlled version.
IntegraSlice is controlled using sealed Liquid Crystal Display (LCD) with associated membrane keypad to set the cutting parameters of blade speed, advance speed and section thickness. There is a rotary brightness control for the cold light source. The IntegraSlice operation is commenced by actuating the two-stage footswitch. The first stage starts the oscillating blade and the second stage starts the advance of the blade.