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Overview

 

• 5 mm linear movement per revolution on each axis
• Absolute lock at 90º (vertical)
• Entire frame is electrically continuous, ideal for Electrophysiology
• Includes the U-frame base plate, two manipulator arms, probe

Features

WPI’s Precision Stereotaxic Instrument is built around the time-proven U-frame design concept, providing stability, and adaptability to most species. Precision alignment ensures accurate placement of electrodes, micropipettes, and other devices. It is ideal for researchers in need of a versatile, reliable instrument for stereotaxic procedures with small animals.

Versatility of positioning

The manipulator arm controls medio-lateral and vertical positioning via lead screws with 80 mm of travel. This allows the fastest positioning possible, consistent with lining up the scales easily at a given coordinate. The antero-posterior movement is controlled via a dovetail slide movement, with 80 mm of travel possible in each direction. A universal joint allows the investigator to change the angle of the probe up to 90° in either the antero-posterior or medio-lateral planes. The locking mechanism will hold any angle position without drift or creep. It also provides an absolute lock at 90° vertical.

Easily read scales

All scales are oriented to be read easily from the open end of the “U”. This is the position from which most scientists prefer to work. The numerals on the scales are clear and easy to read. Precise alignment with facing vernier scales gives accurate resolution to 0.1 mm. Vernier scales can also be augmented with a digital LCD position readout similar to a digital Vernier caliper. This option extends the readable resolution to 10 microns.

Convenient for electrophysiology

The entire Stereotaxic frame including the dovetails, manipulator arms and base are electrically continuous. Grounding of the entire frame including the base plate can be accomplished by connecting the provided grounding stud to earth. This is ideal for electrophysiological studies where the animal and surrounding structures need to be grounded to reduce electrical noise.

Included components

Includes the U-frame base plate, two manipulator arms, standard probe holder with corner clamp, and Rat Adaptor (nose clamp assembly and 45° taper ear bars).

Selection of accessories

Species adaptors are available to fit rat, cat/monkey, mouse, guinea pig and small bird. Probe holders and species adaptors for “U” frame stereotaxic instruments from other manufacturers are generally compatible with the WPI’s stereotaxic frame.

Specifications

Accessories

Citations

Bull, N., Guidi, A., Goedert, M., Martin, K., & Spillantini, M. (2012). Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau. PloS one. Retrieved from https://dx.plos.org/10.1371/journal.pone.0034724

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