NVSL

Overview

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• Manually advance specimen holder and bath chamber
• Slice width range: 50- to 700- microns thick
• Fixed tissues can be sliced down to 20-microns thick

Details

Vibroslice uses a vibrating blade to slice tissues without the trauma produced by other methods. Live brain or other tissues can be cut into slices 50- to 700-microns thick. Fixed tissues can be cut down to 20-micron slices (these need not be embedded or frozen). Particularly useful for improving the access for certain histological reagents (e.g., during processing for horseradish peroxidase). The blade has a lateral displacement of about 1 mm, and its oscillating frequency may be varied between 60 and 4500 rpm. This allows you to achieve clean cuts in tissues of different mechanical consistencies.

Manual model

Model SYS-NVSL offers a manual advance for positioning the specimen holder and bath chamber. Sample positioning on Model SYS-NVSL is motorized. Other features include independent, removable specimen holder and bath chamber, variable advance speed and hands-free operation via a footswitch.

Specifications

Accessories

Citations

Glasgow, S., & Chapman, C. (2013). Muscarinic Depolarization of Layer II Neurons of the Parasubiculum. PloS one. Retrieved from https://dx.plos.org/10.1371/journal.pone.0058901

Glasgow, S., Glovaci, I., Karpowicz, L., & Chapman, C. (2012). Cholinergic suppression of excitatory synaptic transmission in layers II/III of the parasubiculum. Neuroscience. Retrieved from https://www.sciencedirect.com/science/article/pii/S0306452211013248

Gobbi, S., & Farris, S. (2012). INFLUENCE OF CULTIVAR AND PROCESS CONDITIONS ON CRISPNESS OF OSMO-AIR-DRIED APPLE CHIPS. Journal of Food Process  …. Retrieved from https://onlinelibrary.wiley.com/doi/10.1111/j.1745-4530.2010.00626.x/full

Hupp, S., Heimeroth, V., Wippel, C., & Förtsch, C. (2012). Astrocytic tissue remodeling by the meningitis neurotoxin pneumolysin facilitates pathogen tissue penetration and produces interstitial brain edema. Glia. Retrieved from https://onlinelibrary.wiley.com/doi/10.1002/glia.21256/full

Isaev, D., & Ivanchick, G. (2012). Surface charge impact in low-magnesium model of seizure in rat hippocampus. Journal of  …. Retrieved from https://jn.physiology.org/content/107/1/417.short

Kurata, K., & Matsushita, M. (2012). Effect of irreversible electroporation on three-dimensional cell culture model. …  in Medicine and …. Retrieved from https://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6345900

Sparks, D., & Chapman, C. A. (2012). Cholinergic receptor activation induces a relative facilitation of synaptic responses in the entorhinal cortex during theta-and gamma-frequency stimulation of. Neuroscience. Retrieved from https://www.sciencedirect.com/science/article/pii/S0306452212011372

Trinel, D., Picquet, F., Bastide, B., & Canu, M. (2013). Dendritic spine remodeling induced by hindlimb unloading in adult rat sensorimotor cortex. Behavioural brain research. Retrieved from https://www.sciencedirect.com/science/article/pii/S0166432813002155

Veen, D. van der, Shao, J., Xi, Y., Li, L., & Duffield, G. (2012). Cardiac Atrial Circadian Rhythms in PERIOD2:: LUCIFERASE and per1: luc Mice: Amplitude and Phase Responses to Glucocorticoid Signaling and Medium. PloS one. Retrieved from https://dx.plos.org/10.1371/journal.pone.0047692

Wippel, C., Maurer, J., Förtsch, C., Hupp, S., & Bohl, A. (2013). Bacterial Cytolysin during Meningitis Disrupts the Regulation of Glutamate in the Brain, Leading to Synaptic Damage. PLoS  …. Retrieved from https://dx.plos.org/10.1371/journal.ppat.1003380

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