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ISO-NOP3020

ISO-NOP3020

Nitric Oxide Sensor - 30um


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Overview

ISO-NOP3020

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Instruction Manual
/ Download as PDF

  • Requires cable 91580 (sold separate)
  • Response Time:
  • Lowest Detection Limit: 1 nM
  • Sensitivity: 1.4 pA/nM
  • Application: Microvessels

30 micron sensor with exceptional performance

The ISO-NOP30 has a tip diameter of 30 microns and is available in two different tip lengths (ISO-NOP3020 has tip length of 2 mm, ISO-NO3005  has tip length of 0.5 mm). The response is linear over a wide dynamic concentration range of NO. The design is based on a single carbon fiber coated with WPI's NO-selective membrane. A detection limit of approximately 1 nM NO makes these electrodes ideal for use in tissues and microvessels.

The response of a 7μm NO sensor (ISO-NOP007) to successive additions of NO (100nM). Inset shows the linearity of the resulting calibration plot.

Simultaneous measurement of force (top trace) and changes of NO concentration (lower trace) in (A) the rat superior mesenteric artery relaxed with ACh and (B) a small human artery relaxed with ACh and SNAP. In this artery oxyhaemoglobin (oxyHb) partly reversed the increase in NO concentration with only a small change in force. [U. Simonsen, et al., J. Physiol., 1999, 516: 271-282.]

Specifications

Outside Diameter  30μm
Available Length   2mm
Response Time   < 3 seconds  
Lowest Detection Limit/Range 1nM
Nominal Sensitivity-New sensor   ≥1.5pA/nM 
Baseline Drift   none  
Poise Voltage  865mV
Typical Quiescent Baseline Current, 25°C 500pA
Acceptable Baseline Range   500-5000pA  
Polarization Time   1+ hours

 

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Citations

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