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Julian was fantastic, he patiently walked me through the steps for diagnosing issues with our syringe pump. We found it was a simple belt that was broken and he sent out a replacement part the same day.
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ISO-HPO-100 Hydrogen Peroxide Sensor - 100µm (hypodermic sheath)

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ISO-HPO-100H tip ISO-HPO-100H

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ISO-HPO-100 Instruction Manual
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  • For use with Apollo1000, Apollo4000, TBR4100 and TBR1025
  • Requires cable 91580 (sold separate)
  • Response Time: < 5s (90%)
  • Detection Limit: 1nM - 1mM
  • Drift: < 1.0pA/min.
  • Sensitivity: 1 pA/nM
  • Application: Tissue
  • Contains hypodermic sheath for easy insertion into tissue
  • Package of 3


Sensing Hydrogen Peroxide

Hydrogen Peroxide is produced in biological systems by controlled pathways at low concentrations that impact on cell signaling. At higher concentrations inflammatory cells produce local intense amounts of this oxidant to kill pathogens. In the progress of human disease, uncontrolled formation of hydrogen peroxide from the mitochondrial respiratory chain and enzymes, such as xanthine oxidase, can occur (Prof. Victor Darley-Usmar, Univ. of Alabama, personal communication). Despite the recognized importance of this oxidant in biology real-time measurements at low concentration have been difficult. The hydrogen peroxide sensors developed by WPI are designed to compliment existing high sensitivity fluorescent approaches with direct quantitative measurement in biological samples in the low nM range.


The ISO-HPO-100 is a 100 micron tip diameter hydrogen peroxide micro sensor designed for use in tissues and similar applications. The sensor design is based on a flexible "activated" carbon fiber sensing electrode coated with a proprietary membrane that enhances hydrogen peroxide detection.

The ISO-HPO-100H is enclosed in a hypodermic needle. The image below shows the needle tip and enclosed sensor as viewed through a microscope.


These sensors incorporate WPI's proprietary combination electrode technology whereby the hydrogen peroxide sensing element and separate reference electrode are encased within a single Faraday-shielded probe design. This design has been shown to enhance performance during measurements and minimizes overall sensor size.





Our Clients Include:

University College London
Imperial College
University of Cambridge
University of Oxford

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