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Janice Carter, University of Cambridge

The person in WPI I deal with is Julian Williams and he has been very helpful in sorting out any problems we may have and finding items that we require. He is very pleasant to deal with and I have used WPI for the last 8 years and I am very happy with the service that they provide us.
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MechanoCulture FX , 24-well cell culture bioreactor with unaxial stretching and real-time imaging

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MCFX Datasheet
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Key Features

  • Uniaxial stretch of 16 culture wells in a single-use silicone well plate
  • 0.25mm thick membranes for high-magnification imaging using an inverted microscope
  • PC-independent operation
  • User-friendly interface software for specifying simple, cyclic, and intermittent stimulation protocols for download to the device controller

The MCFX uses a single-use flexible silicone well plate to culture cells in much the same environment as a traditional polystyrene well plate. After allowing the cells to develop adhesion to the well bottom, the MCFX can execute a user-specified stretch protocol to the well plate, causing the cells to deform. The well bottoms have similar optical properties to a glass coverslip, permitting high-magnification imaging of the cultured cells. The well plates can be sterilized and the system is suitable for long-term cell culture in a laboratory incubator.

Adhered Cell Monolayer Culture

Single-use silicone well plate.  Cell culture wells are 8mm X 8mm with a 0.25mm thick transparent bottom membrane. The 16 cell culture surfaces are shown in red.

3D Gel Scaffold Culture

The 3D gel culture plate has 18 micro-protrusions on the bottom membrane of each well to secure the gel in place during the stretching protocol.








MechanoCulture B1 - Strainable Substrate for culturing Cells

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University College London
Imperial College
University of Cambridge
University of Oxford

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