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MechanoCulture FX , 24-well cell culture bioreactor with unaxial stretching and real-time imaging

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MCFX Datasheet
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Key Features

  • Uniaxial stretch of 16 culture wells in a single-use silicone well plate
  • 0.25mm thick membranes for high-magnification imaging using an inverted microscope
  • PC-independent operation
  • User-friendly interface software for specifying simple, cyclic, and intermittent stimulation protocols for download to the device controller

The MCFX uses a single-use flexible silicone well plate to culture cells in much the same environment as a traditional polystyrene well plate. After allowing the cells to develop adhesion to the well bottom, the MCFX can execute a user-specified stretch protocol to the well plate, causing the cells to deform. The well bottoms have similar optical properties to a glass coverslip, permitting high-magnification imaging of the cultured cells. The well plates can be sterilized and the system is suitable for long-term cell culture in a laboratory incubator.

Adhered Cell Monolayer Culture

Single-use silicone well plate.  Cell culture wells are 8mm X 8mm with a 0.25mm thick transparent bottom membrane. The 16 cell culture surfaces are shown in red.

3D Gel Scaffold Culture

The 3D gel culture plate has 18 micro-protrusions on the bottom membrane of each well to secure the gel in place during the stretching protocol.








MechanoCulture B1 - Biaxial stimulation of a cells in a monolayer or 3D matrix

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