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Janice Carter, University of Cambridge

The person in WPI I deal with is Julian Williams and he has been very helpful in sorting out any problems we may have and finding items that we require. He is very pleasant to deal with and I have used WPI for the last 8 years and I am very happy with the service that they provide us.
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UMP3-3

UMP3-3

Three UltraMicroPump3 (UMP3) pump heads with SYS-Micro4 Controller


  • Overview
  • Specifications
  • Accessories
  • Citations
  • Related Products

Overview

UMP3-3 Micro4 controller with 3 UMP3 heads (micromanipulator and NANOFIL syringe sold separately) UMP3

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Data Sheet
/ Download as PDF

  • includes (3) UMP3 pumps and (1) SYS-MICRO4 controller
  • Versatile injector uses microsyringes to deliver picoliter volumes
  • Syringes are easily installed, just snap the barrel into the clamps
  • Threaded shaft drives syringe plunger allowing smooth and accurate movement

 

Picoliter volumes

With its digital controller, UltraMicroPump III can dispense as little as 600 picoliters per incremental advance of the syringe piston (using a 0.5μL syringe). Syringes may be filled externally and then inserted into the pump or filled while mounted in the pump. Fluids injected or withdrawn are held entirely within the micro syringe to maintain a low fluid dead volume.

Positioning

For positioning, the UltraMicroPump III may be attached to any of several WPI micropositioners such as the M3301 (manual), DC3001 (motorized), or any manual stereotaxic manipulator.


Smart Controller

An Integral component in the UMPIII system is a microprocessor-based controller, SYS-MICRO4, which provides an "intelligent" and easy-to-use interface to up to four syringe pumps. Operating parameters are set with the membrane key­pad and LCD display. From the key­pad the user can select the following functions: set pump to infusion or withdrawal mode, enter the volume to be infused or withdrawn, rate of delivery, and syringe type as well as synchronize the starting and stopping of any combination of syringe pumps. User parameters can be stored in the device's "non-volatile" memory for instant recall when the unit is powered on. An optional footswitch can be plugged into a connector on the rear of the controller for "hands free" start/stop operation. Computer Control - An RS-232 port on the rear of the controller can be used to connect it to a computer for use with computer control programs.

Specifications

NORMAL MODE

Total # of Steps 20,000(63mm travel)
Minimum Dispensing Volume 0.58nL/step (10μL syringe)
Linear Motion per Step 3.175μm
Weight 325g (11.5 oz.)
Mounting Rod Diameter 7.9mm (0.31 in.)
Controller Power Requirements
2A, 12VDC
Dimensions Ø32mm x 190mm (1.3 in. x 7.5 in.)

 



MICROSTEPPING MODE
Precision is increased eight fold.

Accessories

UMP3

UMP3

UltraMicroPump (head only)

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65085

65085

Replacement Mounting Bar Locking Nut for UMP3

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15867

15867

Footswitch for SYS-Micro4 Controller. Hands-free activation of microinjection pump.

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Citations

Ali, M., & Kim, Y. (2014). Antiviral activity of the inducible humoral immunity and its suppression by eleven BEN family members encoded in< i> Cotesia plutellaebracovirus. Comparative Biochemistry and Physiology Part A:  …. Retrieved from https://www.sciencedirect.com/science/article/pii/S109564331400186X

Al-Salih, H., Fathi, R., Godbold, D., & Tomos, A. (2014). Detection of Uranium Contamination in Acacia Cell Sap by Capillary Zone Electrophoresis (CZE) Technique. Journal of Natural  …. Retrieved from https://www.iiste.org/Journals/index.php/JNSR/article/view/11793

Bass, D., Nizam, Z., & Partain, K. (2014). Amygdala-mediated enhancement of memory for specific events depends on the hippocampus. Neurobiology of learning  …. Retrieved from https://www.sciencedirect.com/science/article/pii/S1074742713002165

Bélanger, S., & Souza, B. de. (2014). Neurovascular Coupling in the Deep Brain Using Confocal Fiber-Optic Endomicroscopy. Neurovascular Coupling …. Retrieved from https://link.springer.com/protocol/10.1007/978-1-4939-0724-3_5

Bellavance, M., Gosselin, D., & Yong, V. (2014). Patrolling monocytes play a critical role in CX3CR1-mediated neuroprotection during excitotoxicity. Brain Structure and  …. Retrieved from https://link.springer.com/article/10.1007/s00429-014-0759-z

Castellano, O., Arji, M., & Sancho, C. (2013). Chronic administration of risperidone in a rat model of schizophrenia: A behavioural, morphological and molecular study. Behavioural brain  …. Retrieved from https://www.sciencedirect.com/science/article/pii/S0166432812008261

Chen, L., Miao, Y., Xu, J., & Wang, X. (2014). The role of low levels of fullerene C60 nanocrystals on enhanced learning and memory of rats through persistent CaMKII activation. Biomaterials. Retrieved from https://www.sciencedirect.com/science/article/pii/S0142961214008394

Donnelley, M., & Morgan, K. (2013). Variability of In Vivo Fluid Dose Distribution in Mouse Airways Is Visualized by High-Speed Synchrotron X-Ray Imaging. Journal of aerosol  …. Retrieved from https://online.liebertpub.com/doi/abs/10.1089/jamp.2012.1007

Donnelley, M., Morgan, K., & Siu, K. (2014). Non-invasive airway health assessment: Synchrotron imaging reveals effects of rehydrating treatments on mucociliary transit in-vivo. Scientific reports. Retrieved from https://www.nature.com/srep/2014/140114/srep03689/full/srep03689.html

Duan, R., Zhang, L., Chen, D., & Yang, F. (2014). Two p90 Ribosomal S6 Kinase Isoforms Are Involved in the Regulation of Mitotic and Meiotic Arrest in Artemia. Journal of Biological  …. Retrieved from https://www.jbc.org/content/289/23/16006.short

Fioravante, D., Chu, Y., & Jong, A. de. (2014). Protein kinase C is a calcium sensor for presynaptic short-term plasticity. eLife. Retrieved from https://elifesciences.org/content/3/e03011.abstract

Georges, J, Zehri, A., & Carlson, E. (2014). Contrast-free microscopic assessment of glioblastoma bioposy specimens prior to biobanking. Neurosurgical  …. Retrieved from https://thejns.org/doi/abs/10.3171/2013.11.FOCUS13478

Georges, JF, & Martirosyan, N. (2014). Sulforhodamine 101 selectively labels human astrocytoma cells in an animal model of glioblastoma. Journal of Clinical  …. Retrieved from https://www.sciencedirect.com/science/article/pii/S0967586814000708

Gosselin, D., Bellavance, M., & Rivest, S. (2013). IL-1RAcPb signaling regulates adaptive mechanisms in neurons that promote their long-term survival following excitotoxic insults. Frontiers in cellular  …. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573345/

Haberl, M., Silva, S. da, & Guest, J. (2014). An anterograde rabies virus vector for high-resolution large-scale reconstruction of 3D neuron morphology. Brain Structure and  …. Retrieved from https://link.springer.com/article/10.1007/s00429-014-0730-z

Hislop, J., & Islam, T. (2014). Rabies virus envelope glycoprotein targets lentiviral vectors to the axonal retrograde pathway in motor neurons. Journal of Biological  …. Retrieved from https://www.jbc.org/content/289/23/16148.short

Lloyd-Burton, S., & York, E. (2013). SPARC Regulates Microgliosis and Functional Recovery following Cortical Ischemia. The Journal of  …. Retrieved from https://www.jneurosci.org/content/33/10/4468.short

Lu, X., Huxley, V., & Kassab, G. (2013). Endothelial barrier dysfunction in diabetic conduit arteries: a novel method to quantify filtration. American Journal of  …. Retrieved from https://ajpheart.physiology.org/content/304/3/H398.short

Ma, Z., Gulia-Nuss, M., Zhang, X., & Brown, M. (2013). Effects of the Botanical Insecticide, Toosendanin, on Blood Digestion and Egg Production by Female Aedes aegypti (Diptera: Culicidae): Topical Application and. Journal of medical entomology. Retrieved from https://www.bioone.org/doi/pdf/10.1603/ME12119

Magableh, A., & Lundy, R. (2014). Somatostatin and Corticotrophin Releasing Hormone Cell Types Are a Major Source of Descending Input From the Forebrain to the Parabrachial Nucleus in Mice. Chemical senses. Retrieved from https://chemse.oxfordjournals.org/content/39/8/673.short

Margolis, D., Lütcke, H., & Helmchen, F. (2014). Chronic Two-Photon Imaging of Neural Activity in the Anesthetized and Awake Behaving Rodent. Optical Imaging of  …. Retrieved from https://link.springer.com/protocol/10.1007/978-1-62703-785-3_10

Marguí, E., Zawisza, B., & Sitko, R. (2014). Trace and ultratrace analysis of liquid samples by X-ray fluorescence spectrometry. TrAC Trends in Analytical Chemistry. Retrieved from https://www.sciencedirect.com/science/article/pii/S0165993613002343

Matsuura, S., Shuvaev, A., & Iizuka, A. (2014). Mesenchymal Stem Cells Ameliorate Cerebellar Pathology in a Mouse Model of Spinocerebellar Ataxia Type 1. The Cerebellum. Retrieved from https://link.springer.com/article/10.1007/s12311-013-0536-1

Montgomery, S., & Narrow, W. (2013). Chronic Neuron-and Age-Selective Down-Regulation of TNF Receptor Expression in Triple-Transgenic Alzheimer’s Disease Mice Leads to Significant Modulation of. The American journal of  …. Retrieved from https://www.sciencedirect.com/science/article/pii/S0002944013002095

Ni, Y., Nawabi, H., & Liu, X. (2014). Characterization of Long Descending Premotor Propriospinal Neurons in the Spinal Cord. The Journal of  …. Retrieved from https://www.jneurosci.org/content/34/28/9404.short

Pierce, A., & Keating, A. (2014). Creating Anatomically Accurate and Reproducible Intracranial Xenografts of Human Brain Tumors. JoVE (Journal of Visualized Experiments). Retrieved from https://www.jove.com/video/52017/creating-anatomically-accurate-reproducible-intracranial-xenografts

Punjabi, M., Arnold, M., & Rüttimann, E. (2014). Circulating Glucagon-like Peptide-1 (GLP-1) Inhibits Eating in Male Rats by Acting in the Hindbrain and Without Inducing Avoidance. …. Retrieved from https://press.endocrine.org/doi/abs/10.1210/en.2013-1447

Puskarjov, M., Ahmad, F., & Khirug, S. (2014). BDNF is required for seizure-induced but not developmental up-regulation of KCC2 in the neonatal hippocampus. …. Retrieved from https://www.sciencedirect.com/science/article/pii/S0028390814003128

Rangel, A., & Race, B. (2013). Non-amyloid and amyloid prion protein deposits in prion-infected mice differ in blockage of interstitial brain fluid. Neuropathology and  …. Retrieved from https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2990.2012.01303.x/full

Rangel, A., Race, B., & Phillips, K. (2014). Distinct patterns of spread of prion infection in brains of mice expressing anchorless or anchored forms of prion protein. Acta  …. Retrieved from https://www.biomedcentral.com/content/pdf/2051-5960-2-8.pdf

Root, D., & Mejias-Aponte, C. (2014). Role of Glutamatergic Projections from Ventral Tegmental Area to Lateral Habenula in Aversive Conditioning. The Journal of  …. Retrieved from https://www.jneurosci.org/content/34/42/13906.short

Saida, H., Matsuzaki, Y., Takayama, K., & Iizuka, A. (2014). One-year follow-up of transgene expression by integrase-defective lentiviral vectors and their therapeutic potential in spinocerebellar ataxia model mice. Gene therapy. Retrieved from https://www.nature.com/gt/journal/v21/n9/abs/gt201460a.html

Salvi, J., Bertaso, F., & Mausset-Bonnefont, A. (2014). RNAi silencing of P/Q-type calcium channels in Purkinje neurons of adult mouse leads to episodic ataxia type 2. Neurobiology of  …. Retrieved from https://www.sciencedirect.com/science/article/pii/S0969996114000941

Siddiqui, A., Sabljic, T., Koeberle, P., & Ball, A. (2014). Downregulation of BM88 After Optic Nerve Injury. …  ophthalmology & visual …. Retrieved from https://www.iovs.org/content/55/3/1919.short

Silberman, Y. (2013). A Corticotropin Releasing Factor Pathway for Ethanol Regulation of the Ventral Tegmental Area in the Bed Nucleus of the Stria Terminalis. The Journal of  …. Retrieved from https://www.jneurosci.org/content/33/3/950.short

Trabalza, A., Eleftheriadou, I., & Sgourou, A. (2014). Enhanced central nervous system transduction with lentiviral vectors pseudotyped with RVG/HIV-1gp41 chimeric envelope glycoproteins. Journal of  …. Retrieved from https://jvi.asm.org/content/88/5/2877.short

Tucci, M., & Dvorkin-Gheva, A. (2014). Performance of compulsive behavior in rats is not a unitary phenomenon–validation of separate functional components in compulsive checking behavior. European Journal of  …. Retrieved from https://onlinelibrary.wiley.com/doi/10.1111/ejn.12652/full

Wen-Ming, M., & Hua-Wei, L. (2013). Chitin-binding proteins of Artemia diapause cysts participate in formation of the embryonic cuticle layer of cyst shells. Biochemical  …. Retrieved from https://www.biochemj.org/bj/449/bj4490285.htm

Yang, J., & Yang, W. (2014). Two p90 Ribosomal S6 Kinase Isoforms. Retrieved from https://devbio.jbc.org/highwire/filestream/1799/field_highwire_article_pdf/0/jbc.M114.553370.full.pdf

Ye, X., Zhao, Y., Zhao, L., Sun, Y., Yang, J., & Yang, W. (2014). Characterization of PHB1 and Its Role in Mitochondrial Maturation and Yolk Platelet Degradation during Development of Artemia Embryos. PloS one. Retrieved from https://dx.plos.org/10.1371/journal.pone.0109152

Zhou, R., Sun, Y., Yang, W., & Yang, F. (2014). Identification and Characterization of a Ste20-Like Kinase in Artemia and Its Role in the Developmental Regulation and Resistance to Environmental Stress. PloS one. Retrieved from https://dx.plos.org/10.1371/journal.pone.0092234.g007

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