MCTX-401

Overview

• Uniaxial compression stimulation during culture
• 6 independent wells
• Cyclic compression stimulation up to 2 Hz
• Max displacement 2 mm
• Load cell options (10–100 N) with stiffness tracking
• Incubator-ready with sterile culture barrier

The MechanoCulture TX (MCTX) mechanical stimulation bioreactor applies controlled uniaxial compression to 3D specimens in six independent culture wells. Designed for incubator use, researchers can program a stimulation protocol, run it in a standard laboratory incubator, and log force and displacement to evaluate how construct stiffness evolves over time.

MechanoCulture TX is commonly used for mechanotransduction studies, engineered tissue conditioning, and long-term culture workflows where repeatable compression stimulation is required. Transparent wells support visual confirmation of specimen loading and optional imaging during stimulation.

Specimens are loaded into a reusable well plate with media, sealed with a flexible sterile barrier, placed on the controller, and run inside the incubator using a saved compression stimulation protocol. The actuation assembly applies uniaxial compression through plungers aligned to each well. The system can monitor the force-displacement data to determine the stiffness profile of each specimen as a function of time. An optional cooling pump can be added to limit actuator heat transfer during long runs.

MechanoCulture TX Models Available

The MechanoCulture TX is available with either a standard well plate or a perfusion well plate to support different compression culture workflows. Both configurations provide the same 6-well compression stimulation platform with load cells, force-displacement data logging, and programmable long-duration loading protocols, while the well plate format changes how media is handled during culture.

• MCTX-400 Standard Plate version for routine compression stimulation, construct conditioning, mechanotransduction studies
• MCTX-401 Perfusion Plate version for long-duration studies needing media exchange or perfusion-style handling.

What's Included

• Reusable well plate with 6 individual wells (PERFUSION)
• Controller for uniaxial compression stimulation
• Six load cells (10 N, 20 N, 50 N, or 100 N)
• Sealing membranes and sealing O-rings (sterile barrier components)
• Sample spacers (1 mm, 2 mm, 5 mm, 10 mm)
• Programming and data download software (lifetime license)

Video

Specifications

Dimensions	16 X 19 X 16 cm
Weight	4.1 kg
Stimulation mode	Uniaxial compression
Specimen Dimensions	Up to 20 mm diameter/width and 25 mm thick
Number of wells	6
Available load cells	10, 20, 50, 100 N
Force Accuracy	Approx. 0.2% of transducer capacity
Maximum Displacement	2 mm
Maximum Velocity	4 mm/s
Maximum Cycle Frequency	2 Hz

Accessories

Citations

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