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EVOM™ Manual

EVOM™ Manual Epithelial Volt Ohm Meter for TEER Measurement

Benefits of the EVOM™ Manual TEER Measurement Device Eliminates errors and reduces experimental processing time Auto data logging eliminates the need to track data by hand The small footprint allows more bench space Easy calibration and verification Footswitch for hands-free recording Prevent data loss with auto save and data recovery when battery is low Easy TEER value calculation by applying a unit area formula to the resistance

WPI’s EVOM™ Manual is the gold standard for delivering stable and repeatable Trans Epithelial Electrical Resistance (TEER) measurements. The EVOM™ Manual qualitatively measures cell monolayer health and quantitatively measures cell confluence by determining an increase or a plateau in tissue resistance detected using our innovative EVOM™ technology. The EVOM™ Manual TEER measurement system produces a low AC current that avoids electrode metal deposits and is specially designed for the non-destructive testing of epithelial monolayer confluence in cell cultures. Additionally, resistance readings are unaffected by membrane capacitance or membrane voltage. WPI’s state of the art EVOM™ technology provides you with real time valuable feedback during experiment measurements.

The EVOM™ Manual delivers improved workflow efficiency, more stable and repeatable measurements versus traditional Trans Epithelial Electrical Resistance (TEER) meters. Providing users with vital feedback during experiment measurements, the EVOM™ Manual’s large screen offers a range of informational views. The new graphical displays for trend analysis and measurement values helps scientists deliver simple, stepwise methodology during experimental measurements. The touch screen interface provides you with an intuitive, easy-to-use menu for configuration.

Eliminating the need to log data by hand, the EVOM™ Manual features automatic data logging for streamlined data collection. When used with the footswitch it enables handsfree recording of measurements

At the heart of the EVOM™ Manual is our latest processor and circuitry, providing users with quick, easy and reliable readings due to its fast stabilization, automatic twenty times sampling average and low noise design. The auto ranging resistance feature allows for fast resistance measurements, and an over-range display feature eliminates false readings. The EVOM™ Manual has adjustable current levels in three fixed ranges with two lower ranges for sensitive membranes and high resistance ranges up to 100 KΩ.

NEW FEATURE:  In addition to the existing capability of data storage on a USB flash drive, the new version of the EVOM™ Manual now provides an option for a more secured mode of data transfer using a Windows® companion application.

Electrodes For The EVOM™ Manual

STX4

The STX4 electrode is the general-purpose electrode for the manually operated EVOM™ meters like the EVOM™ Manual and EVOM3. With an adapter it may also be used with older versions of the EVOM and Millicell® meters. It is balanced and weighted for hands-free operation, and the shallow electrode tips require less fluid than previous hand-held electrodes. Its design offers greater precision when compared with the STX2 and STX3. This electrode is the only one with replaceable blades. This means you never need to chloride the tips, and you may replace the blades instead of the entire electrode. This extends the life of your electrode. The STX4 is designed for use with 24-well plates.

STX HTS

The STX HTS electrodes are designed for high throughput screening, because the tips are much smaller, and the electrode is keyed to fit neatly into the filter wells. The design improves accuracy over the STX2 and STX3, and it is more durable, too. The size of the electrodes and the design reduces the chances of sample contamination. This is an excellent choice for 24- and 96-well plates. (TITLE: Corning 96, Corning Biocoat/Falcon 24, Corning Costar 24, Millipore 96, Mattek 96)

EndOhm

EndOhm cell culture cup chambers are built for stability and reproducibility to 1% tolerance. These chambers are ideal when precision counts. Three sizes are available: 6mm, 12mm and 24mm for 24-, 12- and 6-well plates. The tri-leg supports provide mechanical stability and holds the membrane parallel to the electrodes. The symmetrical electrode pattern disperses the test current uniformly, giving the most accurate reading of all the EVOM electrodes. However, each well must be individually positioned inside the EndOhm chamber to make a reading.

 

The EVOM™ Manual requires an electrode for use. Choose an electrode suitable for your application.

Cell Culture Insert/Transwell Type	Electrode	Advantages	Disadvantages
Removable 24-well	STX4	No need to transfer inserts. Take measurments in the plate.
Removable 24-well	EndOhm-6	Most accurate mode of measurement, because of the larger electrode surface area and the concentric positioning of the electrodes.	Need to transfer inserts into the EndOhm chamber for making measurements.
Removable 12-well	EndOhm-12
Removable 6-well	EndOhm-24
24- or 96-well High Throughput Screening (HTS) Plates	STX HTS	Fits perfectly in the measurment plate. Choose the option based on your specific plate.

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