Patch Clamp

Patch clamp is a technique in electrophysiology used to study ionic currents in individual isolated living cells, tissue sections, or patches of cell membrane. This is achieved in real time using low noise patch clamp amplifiers, data acquisition systems and analysis software. Key applications include the study of excitable cells such as neurons, cardiomyocytes and muscle fibres.

The Sutter dPatch® Digital Patch Amplifier System combines an unmatched sampling rate of up to 5 MHz with noise performance that supports the quietest single-channel recordings and digital architecture for the highest signal fidelity and ultra-stable compensation circuitry. The dPatch represents the most advanced amplifier for electrophysiology on the market today.

The Sutter IPA® family of Integrated Patch Amplifiers, enables efficient, low-noise whole-cell recordings. The IPA system, available with one (IPA) or two recording channels (Double IPA), combines state-of-the-art amplifier technology with fully integrated D/A and A/D conversion and a high speed USB interface. Acquisition, data management, and streamlined analysis are performed using the bundled SutterPatch® Data Acquisition and Analysis Software, built on the foundation of Igor Pro 8 (WaveMetrics, Inc.).

All Sutter Amplifier Systems were designed with the attention to detail our customers expect and appreciate. The faceplates are sculpted and feature recessed connectors. The pipette holder connects to machined aluminum threads designed for the utmost in mechanical stability and improved shielding. Available accessories include expansion panels, which present ampli?er back panel connections at the front of a 19” rack; a machined brass ground point; standard pipette holders made of polycarbonate; premium pipette holders made of quartz, which minimizes thermal expansion (now standard on dPatch Systems).