World Precision Instruments

Search the site by KEYWORD


Quick Finder


Testimonials

Dr Gary Lawrence, Dublin City University

WPI are my preferred supplier for tissue and cell recording instrumentation. In my experience, WPI representatives have an excellent level of technical expertise and they have always responded in a timely manner with the most helpful, patient and instructive advice to aid the development of the o...
read more

EVOM™ Auto

EVOM™ Auto

EVOM™ Auto automates measurements of TEER epithelial or endothelial monolayers cultured on HTS well plates.


EVOM™ Auto Instruction Manual EVOM™ Auto Overview For Drug Discovery
EVOM™ Auto Installation Guide  EVOM™ Auto Brochure

 

World Precision Instruments (WPI), the global leader in TEER technology, is proud to introduce the EVOM™ Auto, our newest entry into our pioneering EVOM family of products. The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening (HTS) 24 and 96-well and plates utilizing our innovative EVOM technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.

Automated measurement of tissue resistance of  transwell cell cultures provides the advantages of speed and precision, minimizes the chances of contamination, and ensures the rapid availability of measured resistance data. EVOM™ Auto produces a low AC current that omits any adverse physiological effects of the measurement technique on the samples and is specially designed for the non-destructive, high throughput screening of epithelial/ endothelial cellular physiology (e.g.,  confluence of cellular monolayers, barrier integrity of cell cultures, cytotoxicity).

Applications

  • Epithelial and Endothelial Barrier Studies
  • Confluence
  • Cytotoxicity
  • Lung Viral Infection
  • Blood Brain Barrier (BBB)
  • Lung in vitro Models for COVID Studies
  • Intestine, Kidney and Liver Tissues

 

Our EVOM™ Auto is a Complete System

  • Most reliable and convenient method of evaluating and monitoring the structural integrity of epithelial tissue culture in vitro
  • High-throughput 24 and 96-well plate system for labs with high volume
  • Unparalleled measurement accuracy with continuous data recording capability
  • Measure cellular activity label-free and real-time
  • 96 well plate electrode array is compatible with a wide variety of 96-well HTS plates: Corning, Millipore, and MatTek
  • 24C electrode array for Corning 24 HTS plates and 24M electrode array for 24 well Millipore 24 HTS plate
  • Easy switch and measurement in different plate types (24 or 96) by swapping electrode array and plate adapters using the same system
  • With web-based software, no operating system or security upgrades are required

Features

Features Advantages Benefits
Electrodes available for 24 or 96-well HTS plates Measure 24 or 96-wells, a column  at a time (electrode array measures a column). Save time by automating your process and move through a plate quickly.
Easy switch options for different plate types By simply plugging in the right electrode array and matching plate adapter key, fast and easy switch between different HTS plate types (e.g., Corning 24, Corning 96) is possible. The users can perform experiments on different platforms (24 or 96 HTS plates or different 96 HTSs) analyze samples using the same system.  
Automate your measurements Streamline your workflow. Minimize human errors.
Three rinse locations You may rinse your electrodes multiple times during a measuring sequence. Take control of your protocol and define the sequence you need.
Crash protection System automatically detects a misalignment and pauses measurements to prevent equipment damage. Minimize probe damage and avoids costly repairs.
Auto-detection of electrode head System automatically detects your electrode and configures its position and software options for your plate. Hardware setup is easy and requires no configuration.
Intuitive touchscreen interface with browser-based software Programming your sequences is simple with simple selection options. Easy-to-navigate system saves time when configuring sequences.
Confirm or create a custom plate profile Can adjust the programmed coordinates. With complete control of the system, you can fine tune the programming as desired (e.g., plate type, sample depth).
Ability to save three plate coordinates per plate type (. e.g., Corning 96) Multiple (three) users can operate the instrument using their individual saved settings. Date and time stamps of the user plate profile changes help to keep track if the plate profiles were changed. Ensure consistent and error free measurements. 
Store all your data or export to Excel You can analyze your data in a manner suitable to your workflow. Flexibility to access and manage your data.

 

System Includes

  • EVOM™ Auto (TEER Measurement System includes the Autosampler
  • HTS Electrode Array - either 96 HTS or 24C (Corning) HTS or 24M (Millipore) depending on selected item
  • Interface Unit and Cable
  • Control iPad with software

 

System Part Numbers
(includes an electrode array)
Product Description
EVA-MT-03-01 EVOM Auto For TEER Measurement in 96 HTS Plate
EVA-MT-03-02 EVOM Auto For TEER Measurement in 24 Corning HTS Plate
EVA-MT-03-03 EVOM Auto For TEER Measurement in 24 Millipore HTS Plate

 

Specifications

Type Description
Autosampler Dimensions (W×D×H) 40 x 25 x 21 cm
Autosampler Weight 7 Kg
CE Certified Yes
Compatibility
  • Corning, Millipore, MatTek 96-well
  • HTS Plates with 96 electrode array
  • Corning 24 HTS Plates with 24C electrode array
  • Millipore 24 HTS Plates with 24M electrode array
Resistance Range 10KΩ, 50KΩ, 100KΩ
Number of Rinse Stations 3
Electrode Array 
  • Array 8 pair of (1.2 mm φ) Electrodes: 96 well array
  • Array 4 pair of (1.2 mm φ) Electrodes:  24 well array 
Minimum Sample Reading Time 1 Second
Control Device for Running Software Tablet, Laptop, Desktop with Wi-Fi adapter
Output Data CSV/Microsoft® Excel

 

EVOM™ Auto Electrode Array

With additional electrode arrays, the same system can be used for other plate types

Electrode Array Part Numbers Product Description
EVA-EL-03-01 EVOM Auto 96 HTS Electrode Array For TEER
EVA-EL-03-02 EVOM Auto 24C HTS Electrode Array For TEER
EVA-EL-03-03 EVOM Auto 24M HTS Electrode Array For TEER

*24C = Corning 24                 

*24M = Millipore 24

 

EVOM™ Auto Resources

EVOM™ Auto Resources   TEER Knowledge Base



Choose Quantity
EVA-MT-03-01

EVA-MT-03-01

EVOM Auto For TEER Measurement in 96 HTS Plate

System includes:

  • EVOM™ Auto (TEER Measurement System includes the Autosampler
  • HTS Electrode Array for 96 HTS Plates
  • Interface Unit and Cable
  • Control iPad with software


Choose Quantity
EVA-MT-03-02

EVA-MT-03-02

EVOM Auto For TEER Measurement in Corning 24 HTS Plates

System includes:

  • EVOM™ Auto (TEER Measurement System includes the Autosampler
  • HTS Electrode Array for Corning 24 HTS Plates
  • Interface Unit and Cable
  • Control iPad with software


Choose Quantity
EVA-MT-03-03

EVA-MT-03-03

EVOM Auto For TEER Measurement in Millipore 24 HTS Plates

System includes:

  • EVOM™ Auto (TEER Measurement System includes the Autosampler
  • HTS Electrode Array for Millipore 24 HTS Plates
  • Interface Unit and Cable
  • Control iPad with software


Choose Quantity
EVA-EL-03-01

EVA-EL-03-01

EVOM Auto 96 HTS Electrode Array For TEER

Includes

  • Depth Adjustment Fixture Included - 1 x C96 (for Corning 96); 1 x M96 (for Millipore 96); 1 x MT 96 (for MatTek 96)
  • Plate Adapter Key Included - 2 x C96/ MT96 Adapter for Corning and Mattek 96 HTS; 2 x M96 Adapter for Millipore 96 HTS Plates 

Notes

  • The electrode array is a consumable and includes a 90-day warranty
  • Two identical plate adapter keys and one depth adjustment fixture are included per matching plate type. One plate adapter is needed and a 2nd one is provided as a spare.
  • If two different plate types are listed for the plate adapter key, it means both plate types can be used with the same plate adapter key. Example: C24/M24 plate adapter key is used for Corning 24 and Millipore 24 well HTS plates.


Choose Quantity
EVA-EL-03-02

EVA-EL-03-02

EVOM Auto 24 Corning HTS Electrode Array For TEER

Includes

  • Depth Adjustment Fixture Included - 1 x C24 (for Corning 24)
  • Plate Adapter Key Included - 2 x C24/ MT24 Adapter for Corning 24 and Mattek 24 HTS Plates

Notes

  • The electrode array is a consumable and includes a 90-day warranty
  • Two identical plate adapter keys and one depth adjustment fixture are included per matching plate type. One plate adapter is needed and a 2nd one is provided as a spare.
  • If two different plate types are listed for the plate adapter key, it means both plate types can be used with the same plate adapter key. Example: C24/M24 plate adapter key is used for Corning 24 and Millipore 24 well HTS plates.


Choose Quantity
EVA-EL-03-03

EVA-EL-03-03

EVOM Auto 24 Millipore HTS Electrode Array For TEER

Includes

  • Depth Adjustment Fixture Included - 1 x M24 (for Millipore 24)
  • Plate Adapter Key Included - 2 x C24/ MT24 Adapter for Corning 24 and Mattek 24 HTS Plates

Notes

  • The electrode array is a consumable and includes a 90-day warranty
  • Two identical plate adapter keys and one depth adjustment fixture are included per matching plate type. One plate adapter is needed and a 2nd one is provided as a spare.
  • If two different plate types are listed for the plate adapter key, it means both plate types can be used with the same plate adapter key. Example: C24/M24 plate adapter key is used for Corning 24 and Millipore 24 well HTS plates.


Choose Quantity
EVA-AC-03-02-25

EVA-AC-03-02-25

Sterile Disposable Rinse Station Insert of EVOM™ Auto 25/pk

These disposable rinse stations fit conveniently inside the rinse station of the EVOM™ Auto Automated TEER Measurement system for effective and convenient electrode cleaning, disinfection, and maintenance.

  • Individually Sterile rinse station inserts
  • Dispose after use
  • Use a fresh sterile one after each sample plate reading or before switching to different set of sample plates
  • Recommended for convenient and effective electrode cleaning, disinfection and maintenance


Choose Quantity
EVA-AC-03-02-10

EVA-AC-03-02-10

Sterile Disposable Rinse Station Insert of EVOM™ Auto 10/pk

These disposable rinse stations fit conveniently inside the rinse station of the EVOM™ Auto Automated TEER Measurement system for effective and convenient electrode cleaning, disinfection, and maintenance.

  • Individually Sterile rinse station inserts
  • Dispose after use
  • Use a fresh sterile one after each sample plate reading or before switching to different set of sample plates
  • Recommended for convenient and effective electrode cleaning, disinfection and maintenance

Our Clients Include:

GlaxoSmithKline
University College London
Novartis
Imperial College
University of Cambridge
University of Oxford

Keep in Touch

We promise NEVER to share your details with anyone. You can opt out at any time.