Multi-Port Measurement Chamber Temperature stabilized four-port closed chamber for measurements of nitric oxide, oxygen hydrogen peroxide and other species in cell culture ● Four port (WPI #NOCHM-4) chamber accommodates WPI’s 2-mm sensors for nitric oxide (ISO-NOP), oxygen (OXELP), hydrogen peroxide, and WPI’s KWIK-TIP ion selective electrodes in combination with WPI’s 2 mm Dri-Ref™ reference electrodes. ● Two additional top ports for injection of reagents using WPI’s MicroFil™ syringe needles ● Closed chamber design greatly reduces the surface area of the solution exposed to air ● One top port and up to three side ports configuration provides adequate space for convenient sample and electrode manipulation ● Temperature control through an external circulating bath ● The chamber can be used for nitric oxide and other species calibration at temperatures from 4-40 ºC NOCHM-4 Four-Port Closed Chamber, for use with WPI’s 2.0 mm electrodes (e.g., ISO-NOP and OXELP, etc.) NOCHM-P Spare Plug-adapter for ISO-NOP nitric oxide electrode 800100-5 Spare Center Chamber Gasket (package of 5) BIOSENSING S-nitrosoglutathione Pre-polarizer Keep extra NO sensors ready to use GSNO has been identified in vivo as a potential storage and transport vehicle for NO in the body. GSNO has been used in clinical trials to treat a form of preeclampsia and to prevent platelet aggregation. It also has considerable potential as NO donor in medicine. M.W.336.3 • C10H16N4O7S • Purity > 98% • Soluble in water or DMSO • Storage: -20°C GSNO-50 GSNO 50 mg vial GSNO-100 GSNO 100 mg vial ISO-NOP Rejuvenator After an ISO-NOP 2-mm sensor is used for long periods, sensitivity may become reduced and response time may increase. This little device can restore ISO-NOP performance to original levels by applying an electric waveform for a few seconds. 9v alkaline battery included. Achieve a stable background current quickly. This small battery-powered device applies a potential to the NO electrode equivalent to the potential applied by the ISO-NO meter. Consequently, a sensor which has been connected to the activator may be transferred to the meter for immediate use. For use with all WPI NO electrodes. S-Nitroso-N-acetyl-Dpenicillamine SNAP is a stable green crystalline S-nitrosothiol compound that mimics the action of nitric oxide in vivo. It has vasodilatory properties and has been shown to relax isolated bovine coronary artery rings by activating soluble granulate cyclase. This reagent also actuates apoptosis in mouse thymocytes and has been accounted for reversible inactivation of protein Kinase C. SNAP can be used for calibration of all WPI NO sensors. JUV ISO-NOP Rejuvenator M.W. 220.2 • Purity > 98% by NMR or TLC SNAP25 SNAP50 SNAP100 SNAP, 25 mg vial SNAP, 50 mg vial SNAP, 100 mg vial NSA-3 ISO-NO Activator UK: Tel: +44 (0)1462 424700 • wpiuk@wpi-europe.com World Precision Instruments www.wpiinc.com Germany: Tel: +49 (0)30-6188845 • wpide@wpi-europe.com US: Tel: 941-371-1003 • sales@wpiinc.com 67