Horizontal Tissue Bath Research system for higher throughput of complex pharmacological/physiological assays the electronics, reduces the bench space requirement up to 4-fold when compared with standard 4-channel organ baths. MUSCLE PHYSIOLOGY Versatile System The SI-HTB combines advanced physiological techniques with the throughput needed in pharmacological assays in one flexible platform. Upgrades to four or more channels are easy and economical. The motor option (SI-MOT) turns your system into a tissue work-out station with isotonic, auxotonic and eccentric force measurement capabilities. Nearly all established myomechnical tests from stretch-release to workloops and muscle fatigue are now possible in a single organ bath system. Some of these procedures require a length change solution (software/hardware) like WPI’s MDAC package. Future is Now The new SI-H Horizontal Tissue/Organ Bath system (SI-HTB) combines the ease of use and productivity of a traditional vertical organ bath with the more advantageous features of single tissue physiology platforms. ● Two channel system for increased productivity, easily expanded to add channels ● Fully independent heating and fluid control for each channel ● Low profile/small footprint ● Variable volume, chemically inert teflon bath with shape configurations from variable to fixed 500µL–10mL ● Modular, space-saving, blade-style electronics (Control up to 4 channels with the electronics in one chassis) ● Large variety of force transducers covering mN–N forces, all with lifetime warranty ● Can be combined with automated fluid control systems ● Add a linear motor and controller (SI-MOT) to perform mechanical, electrophysiological and optical techniques, inculding isometric (standard), isotonic, eccentric and auxotonic ● Add an electrometer like the WPI Duo773 or Electro705 ● Add the multi-purpose Biofluorimeter (SIBF-100) for tissue fluorescence (calcium, NOx, ROS). See page 6. Multiple Bath Options The SI-HTB system breaks through the (large) volume limitations of the traditional organ bath, allowing volumes as low as 500µL in an inert, teflon-based bath. The bath design allows multiple shape options for thick, long, flat and thin tissue. When pharmaceuticals are available in precious, small amounts, you will appreciate this standard feature. A wide range of transducers and tissue mounting supports complement this freedom of tissue shape, volume and size. The solid horizontal tissue bath design is ideal for combination with electrophysiology on the same platform. Intracellular measurements can share the stable solid base of the bath system. WPI’s new fiber-optic based, multi-channel Biofluorimeter allows for tissue fluorescence measurements (calcium, NO, ROS) on the SIHTB platform. Now, you can design a system to meet your needs and budget. And, it is fully upgradeable in the future. Low Profile The low profile and small footprint of the bath system, combined with the modular, space-saving, chassis-mounted design of SI-HTB2 Options WPI’s 16-bit, high speed, Labview-based Muscle Data Acquisition system SI-LABTRAXMDAC is perfect for this platform. 2-Channel SI-HTB platform for isometric force (1) SI-KGX Force Trandsucers (2) SI-BAM21LCB Optical Force Transducer Amplifiers (2) SI-TCM2B 2-Channel Temperature Controller (1) Signal Conditioning Amplifier System Chassis (1) 2-Channel SI-HTB platform for isometric force (2) SI-KGX Force Trandsucers (4) SI-BAM21LCB Optical Force Transducer Amplifiers (4) SI-TCM2B 2-Channel Temperature Controller (2) Signal Conditioning Amplifier System Chassis (1) 2-Channel SI-HTB platform for isometric force (1) SI-KGX Force Trandsucers (2) SI-BAM21LCB Optical Force Transducer Amplifiers (2) SI-TCM2B 2-Channel Temperature Controller (1) SI-MOT Linear motor with controllers (SI-MOTDB) (2) SI-AOSUB Anti-oscillation Unit (2) Signal Conditioning Amplifier System Chassis (1) MDAC Data Acquistion software (1) 2-Channel SI-HTB platform for isometric force (2) SI-KGX Force Trandsucers (4) SI-BAM21LCB Optical Force Transducer Amplifiers (4) SI-TCM2B 2-Channel Temperature Controller (2) SI-MOT Linear motor with controllers (SI-MOTDB) (4) SI-AOSUB Anti-oscillation Unit (4) Signal Conditioning Amplifier System Chassis (2) MDAC Data Acquistion software (1) www.wpiinc.com Germany: Tel: +49 (0)30-6188845 • wpide@wpi-europe.com US: Tel: 941-371-1003 • sales@wpiinc.com Horizontal Tissue Bath, 2-Channel System SI-HTB4 Horizontal Tissue Bath, 4-Channel System SI-HTB2M Horizontal Tissue Bath, 2-Channel Motorized System SI-HTB4M Horizontal Tissue Bath, 4-Channel Motorized System UK: Tel: +44 (0)1462 424700 • wpiuk@wpi-europe.com World Precision Instruments 5